• CEA,  CEA/CH,  CH,  Choroidal Hypoplasia,  Health

    CEA/CH

    Collie eye anomaly: a congenital syndrome of ocular anomalies characterized by bilateral and often symmetrical defects including any combination of choroidal hypoplasia, coloboma and retinal detachment(s). (From the OFA Eye Disease Glossary) Choroidal hypoplasia: a congenital, inherited, non-progressive defect primarily affecting the choroid resulting in some or all of the following: decreased or lack of pigment in the retinal pigment epithelium or choroid, tapetal thinning and reduced or abnormal choroidal blood vessels. (From the OFA Eye Disease Glossary) Coloboma: a congenital abnormality in ocular development usually characterized by focal absence of tissue, commonly (though not exclusively) located at the 6 o’clock position associated with failure of closure of the optic fissure. (From the…

  • Health,  Patella

    Patellar Luxation

    Subluxated patellas are not uncommon in the breed, and therefore it is important for puppies to have their patellas examined at the well puppy checkup and also certified at one year by an OFA exam. Patella certification is one of the requirements to get a CHIC number. (See Resources for more information.) RESEARCH & ARTICLES What is Patellar Luxation? (OFA) – In patellar luxation, the kneecap luxates, or pops out of place, either in a medial or lateral position.

  • Health

    Epilepsy

    Epilepsy has a long history in this breed, and while careful breeding has helped lessen the numbers, it is still something that breeders should be thoughtful about. RESEARCH & ARTICLES Canine Epilepsy: Demystifying The Myths (Dr. Giunio Cherubini, DVM, DECVN) Epilepsy is not a specific disease, but rather a disorder of aberrant neural connections that can have the widest range of clinical manifestations, from simple “fly-catching” or other unusual head and body movements, to the generalized tonic-clonic contraction with associated incontinence and loss of consciousness. ADAM23 is a common risk gene for canine idiopathic epilepsy (multiple authors) – In this study, we aimed to identify new IE loci by GWA…

  • Health,  Legg Calves Perthes,  Lumbar Transitional Vertebrae

    Legg Calves Perthes & Lumbar Transitional Vertebrae

    While these disorders are not necessarily common in Pyrenean Shepherds, they have occurred in the breed. RESEARCH & ARTICLES What is Legg Calves Perthes Disease? Legg-Calve-Perthes Disease (LCP) is a disorder of hip joint conformation occurring in both humans and dogs. In dogs, it is most often seen in the miniature and toy breeds between the ages of 4 months to a year. The Genetic Background of Lumbosacral Transitional Vertebrae in Dogs (Hannes T. Lohi, PhD; The Folkhälsan Institute of Genetics)

  • HD,  Health,  Hip Dysplasia

    Hip Dysplasia

    Unfortunately this health issue is not uncommon in the breed in not only North America, but around the world. (Please be aware that actual numbers of cases of HD in Pyrenean Shepherds is higher than what the OFA percentage statistics reflect, because OFA does not require abnormal results to be submitted by veterinarians or owners.) Hip certification is one of the requirements to get a CHIC number. (See Resources for more information.) RESEARCH & ARTICLES What is Canine Hip Dysplasia? (HD) Canine Hip Dysplasia typically develops because of an abnormally developed hip joint. Measuring Hip Joint Laxity ( PennHip)

  • Mitral Valve Disease,  PDA

    PDA & Mitral Valve Disease

    PDA is not uncommon in Pyrenean Shepherds and is usually identifiable before puppies go to their new homes. Because of this it is important for breeders to make sure that all of the puppies in their litters have puppy wellness visits with a veterinarian before they are placed. RESEARCH & ARTICLES Patent Ductus Arteriosus (Cornell University) Patent ductus arteriosus (also called PDA) is a birth defect in the heart. An Everyday Approach to Canine Degenerative Mitral Valve Disease (Mark A. Oyama, DVM, Diplomate ACVIM [Cardiology]) Degenerative mitral valve disease (DMVD) is a common canine cardiac disease; approximately 30% of dogs over age 10 possess the characteristic left-sided systolic murmur of…

  • Health,  PRA,  PRA-prcd,  Progressive Rod-Cone Degeneration

    Progressive Rod-Cone Degeneration (PRA-prcd)

    Although not common, this eye issue is found in the breed around the world. Thankfully there is a DNA test that is available for Pyrenean Shepherds to identify dogs, in addition to it being diagnosable why canine ophthalmologists. Progressive retinal atrophy (PRA): an umbrella term used to describe a group of inherited dysplastic, dystrophic, or degenerative disease of the retinal visual cells (photoreceptors, retinal pigment epithelium, or both). (From OFA Eye Disease Glossary) Progressive rod-cone degeneration (PRCD): Typically refers to recessively inherited generalized loss of rod photoreceptors followed by cone degeneration. Many different genetic mutations result in a similar phenotypic presentation. (From OFA Eye Disease Glossary) DNA Testing PRA – UC Davis…

  • Health,  HUU,  Hyperuricosuria

    Hyperuricosuria (HUU)

    Hyperuricosuria is elevated levels of uric acid in the urine that predisposes dogs to form stones in their bladders or sometimes kidneys. While not common in the breed, thankfully we do have a DNA test to screen for it. It is a simple autosomal recessive, meaning that if a dog is affected that both sire and dam are either carriers to affected. DNA TESTING HUU – UC Davis (Listed for Pyrenean Shepherds) Genetic Test for Canine Hyperuricosuria (AKC CHF) – Hyperuricosuria means elevated levels of uric acid in the urine. This trait predisposes dogs to form stones in their bladders or sometimes kidneys. These stones often must be removed surgically…

  • Degenerative Myelopathy,  DM,  Health

    Degenerative Myelopathy (DM)

    A neurodegenerative disease affecting older dogs beginning with paralysis of the pelvic limbs, that is fatal. Thankfully we have a DNA test that is approved for Pyrenean Shepherds. DNA TESTING DM – UC Davis (Listed for Pyrenean Shepherds) Research & Articles What is Degenerative Myelopathy? (University of MO) – Degenerative myelopathy (DM) is a fatal neurodegenerative disease that affects older dogs. It initially results in paralysis of the pelvic limbs but progresses to affect all limbs.

  • Coat,  Color

    Coat & Color

    A fascinating topic for all those interested in breeding dogs. The Pyrenean Shepherd has a number of modifiers that make for a large range of variations. DNA TESTING DNA Test: Coat Color – UC Davis DNA Test: Coat Furnishings & Improper Coat – UC Davis DNA Test: Coat Length – UC Davis DNA Test: Coat Curl – UC Davis DNA Test: Coat Intensity Dilution – UC Davis (All DNA tests listed are listed for Pyrenean Shepherds) Research & Articles More to come…

  • Coat,  Color,  Merle

    Merle

    The merling gene is not only beautiful, but important to understand, since just like in all breeds, two copies of this gene (homozygous merle) can produce serious health issues. Although there is some misinformation about this within the Pyrenean Shepherd community, the gene for merling in the Pyrenean Shepherd is that same gene as in other breeds, so it does cause the same health defects. (See research article below.) DNA TESTING Merle – UC Davis (Listed for Pyrenean Shepherds) RESEARCH & ARTICLES Merle – SINE Insertion from Mc – Mh (Mary Langevin) An important resource concerning the merling genes. Merle phenotypes in dogs – SILV SINE insertions from Mc to Mh (Mary…